Synthesis and properties of oligonucleotides containing 8-bromo-2'-deoxyguanosine.
نویسندگان
چکیده
The preparation of oligonucleotides containing 8-bromo-2'-deoxyguanosine is described. Substitution of G by 8-bromoguanine on an alternating CG decamer stabilizes the Z-form in such a way that the B-form was not observed. Melting temperatures showed that duplexes in which 8-bromo-2'-deoxyguanosine paired with natural bases were much less stable.
منابع مشابه
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ورودعنوان ژورنال:
- Nucleosides, nucleotides & nucleic acids
دوره 20 3 شماره
صفحات -
تاریخ انتشار 2001